Pat Riley to Danny Ainge: Shut up

NEW ORLEANS (AP) ? Miami Heat President Pat Riley has added another chapter to his rivalry with the Boston Celtics.

After LeBron James complained about calls and Boston Celtics president of basketball operations Danny Ainge chided him for it, Riley lashed back Friday night.

Riley's response: "Danny Ainge needs to shut the (expletive) up and manage his own team."

This saga started Wednesday after Miami's 27-game winning streak ended in Chicago. James told reporters that night that he does not believe some of the hard fouls he takes are "basketball plays." A day later, Ainge told Boston radio station WEEI that "it's almost embarrassing that LeBron would complain about officiating."

Riley was clearly irked, calling Ainge "the biggest whiner going when he was a player."

The Heat and Celtics play April 12 in Miami.

Miami beat New Orleans 108-89 on Friday night, with James leading the way with 36 points. When informed afterward of the statement, James said he appreciated Riley having his back.

"That's who we are," James said. "We ride together, all of us, from the top to the bottom. We all protect each other on and off the floor and it was big-time to see that."

Source: http://news.yahoo.com/pat-riley-danny-ainge-shut-010424469--spt.html

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Brain scans might predict future criminal behavior

Friday, March 29, 2013

A new study conducted by The Mind Research Network in Albuquerque, N.M., shows that neuroimaging data can predict the likelihood of whether a criminal will reoffend following release from prison.

The paper, which is to be published in the Proceedings of the National Academy of Sciences, studied impulsive and antisocial behavior and centered on the anterior cingulate cortex (ACC), a portion of the brain that deals with regulating behavior and impulsivity.

The study demonstrated that inmates with relatively low anterior cingulate activity were twice as likely to reoffend than inmates with high-brain activity in this region.

"These findings have incredibly significant ramifications for the future of how our society deals with criminal justice and offenders," said Dr. Kent A. Kiehl, who was senior author on the study and is director of mobile imaging at MRN and an associate professor of psychology at the University of New Mexico. "Not only does this study give us a tool to predict which criminals may reoffend and which ones will not reoffend, it also provides a path forward for steering offenders into more effective targeted therapies to reduce the risk of future criminal activity."

The study looked at 96 adult male criminal offenders aged 20-52 who volunteered to participate in research studies. This study population was followed over a period of up to four years after inmates were released from prison.

"These results point the way toward a promising method of neuroprediction with great practical potential in the legal system," said Dr. Walter Sinnott-Armstrong, Stillman Professor of Practical Ethics in the Philosophy Department and the Kenan Institute for Ethics at Duke University, who collaborated on the study. "Much more work needs to be done, but this line of research could help to make our criminal justice system more effective."

The study used the Mind Research Network's Mobile Magnetic Resonance Imaging (MRI) System to collect neuroimaging data as the inmate volunteers completed a series of mental tests.

"People who reoffended were much more likely to have lower activity in the anterior cingulate cortices than those who had higher functioning ACCs," Kiehl said. "This means we can see on an MRI a part of the brain that might not be working correctly -- giving us a look into who is more likely to demonstrate impulsive and anti-social behavior that leads to re-arrest."

The anterior cingulate cortex of the brain is "associated with error processing, conflict monitoring, response selection, and avoidance learning," according to the paper. People who have this area of the brain damaged have been "shown to produce changes in disinhibition, apathy, and aggressiveness. Indeed, ACC-damaged patients have been classed in the 'acquired psychopathic personality' genre."

Kiehl says he is working on developing treatments that increase activity within the ACC to attempt to treat the high-risk offenders.

###

You can view the paper by clicking here: http://www.pnas.org/cgi/doi/10.1073/pnas.1219302110.

Duke University: http://www.duke.edu

Thanks to Duke University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127523/Brain_scans_might_predict_future_criminal_behavior

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Tobias Dustin Summers Is Main Suspect In 10-Year-Old Girl Abduction Case

Rachel Koechner, Zoee Sandner

In this undated photo released by Chariton County Sheriff's office, Rachel Koechner and her 4-year-old daughter Zoee Sandner are shown. The central Missouri woman who has been missing with her daughter for four days called her boyfriend from a suburban Kansas City motel but was gone when police arrived to check on her. Authorities say they're believed to be with Koechner's former husband and are considered endangered because of previous domestic violence incidents. (AP Photo/Chariton County Sheriff's Office)

Jaray Wilson

Jaray Mickell Wilson, 16, is missing from Cleveland, Ohio. She was last seen in Weatherford in Custer County, Oklahoma on Oct. 15. She is currently listed as a runaway, but but authorities believe she may have been trafficked. Wilson is 5' 2" and weighs 95 pounds with green eyes, black hair with blond streak on the left side, and has three piercings on her bottom lip. Wilson has been entered into the National Crime Information Center Database as a runaway, according to the Sheriff's Office. If you have any information, call the Custer County Sheriff's Office at (580)-323-1616. (Missing Persons Of America)

Natasha Rymarczuk

Natash Rymarczuk has been missing since 10/12/12. She is 17, with blonde hair, brown eyes, and is 5' 7" tall. Natasha was last seen wearing a red Arby's polo shirt and black pants in the Largo, FL area. <a href="http://www.facebook.com/natashacomehome/posts/135304153285040" target="_hplink">(Facebook: Natasha Come Home)</a>

Shawna Hansen

Shawna Hansen, 17, left her north Marysville, Washington home on October 2. Authorities said Hansen has the developmental age of a 10 or 11-year-old. Hansen is about 4-foot-6, 90 pounds, with short, brown hair and brown eyes. She was last seen wearing jeans, black jacket, and a pink and white T-shirt. She is possibly carrying a black, white and blue backpack and may be riding a pink and black "Next" BMX-style bike. Anyone with information on Shawna Hansen's whereabouts is asked to call Marysville police at 360-363-8350.

Austan Tyler Stone

Austan Tyler Stone, 16, was last seen in Post Falls, Idaho on Sept. 10, when he left for school. According to a Facebook page maintained by his family, his cellphone was briefly activated in Modesto, Calif. The Post Falls Police Department has Stone listed as a <a href="http://www.spokesman.com/blogs/sirens/2012/oct/03/family-seeks-information-missing-teen/" target="_hplink">runaway juvenile</a>. Stone is 5-foot-6 and 130 pounds with green eyes and brownish-blonde hair. Anyone with information on his whereabouts is asked to contact the Post Falls Police Department at 208-773-3517 or the Kottenai County Sheriff's Department at 208-446-1300 and refer to Case Number: 12-23395.

Jamal Omar Briggs

Jamal Omar Briggs, 14, was last seen in Roanoke Rapids, North Carolina, on Sept. 26. Detectives with the Roanoke Rapids Police Department said they have no evidence of abduction or foul play. Briggs is described as a black male, 5-feet, 3-inches tall, weighing 135 pounds. He was last seen wearing a red heavy shirt, black jeans and black Jordan tennis shoes. Anyone with information regarding Briggs' whereabouts is asked to call the Roanoke Rapids Police Department at 252-326-3938.

Michael Suarez Jr.

Michael Suarez Jr., 19, was last seen on August 31, at his 61st St. home in Mapleton, New York. According to his aunt, Linda Suarez, her nephew is schizophrenic and he has not had his medication. Anyone with information in this case is asked to contact the Crime Stoppers hotline at 1-800-577-TIPS, or text CRIMES and then enter TIP577.

Christopher Milton Dansby

Christopher, who has been missing since May 18, 1989, was last seen in a park located on 114th Street and Lenox Avenue in Manhattan, New York. He has a birthmark shaped like a figure "8" on his neck. He was 2 years old when he went missing.

Kathryn Pratts

Kathryn, 16 of Staten Island, New York, has been missing since Nov. 24, 2010. Her tongue is pierced and she has a scar over her left eyebrow. Kathryn may go by the nickname Kat or Kathy.

Caelan Cyrus-Howard

Caelan, of Brooklyn, New York, was last seen with his non-custodial mother on 02/21/2002. He has a scar on his forehead and his hair is braided. Caelan was last seen wearing blue jeans, a blue polo shirt and black "ACG" boots. He may be in need of medical attention. Mother and child may have traveled to Trinidad and Tobago.

Jassmyn Carr

Jassmyn, 17, is a runaway. She has been missing since Jan. 13, 2012 and was last seen wearing a white blouse, black pants, gray and purple high top sneakers and a red Old Navy pea coat with large black buttons. Jassmyn, from Queens, New York originally, may be traveling to Virginia

Jeremiah George Huger

Jeremiah George Huger, who has been missing since June of 1985, was playing in his yard in the Bronx, New York, with other children when an unknown black male called to the child and then grabbed him. Jeremiah, who was 4 when he disappeared, has a 1 1/2" scar on his left forearm. He was last seen wearing a light blue shirt, dark blue shorts, and white sneakers.

Shauntae Hope Marks

Shauntae Hope Marks, 15, was last seen on the evening of May 4, 2012, at the Mary Manor apartment complex in Ft. Thompson, South Dakota. According to Fort Thompson police, Marks was distraught over a recent relationship and had made comments threatening to harm herself. Marks is described as a Native American female who is 5-foot-7 and weighs about 170 pounds. She has black shoulder-length hair and brown eyes and wears glasses. Marks was last seen wearing blue jeans, a white shirt with stripes, a black and gray hoodie, and blue Etnies brand tennis shoes. Anyone with information on Shauntae Marks' whereabouts is asked to call Fort Thompson police at 605-245-2351 or 888-337-2388.

Timothy Pitzen

This image from Facebook shows missing 7-year-old Timothy Pitzen. Timothy is missing from Aurora, Ill., but was last seen at a water park in Wisconsin Dells, Wis. He was last known to be in the company of his mother, who has since been found deceased in Rockford, Ill.

Amir Jennings

Amir Jennings, 1, has been missing from Columbia, S.C., since Nov. 24, 2011. Family members originally filed a missing persons report for Amir and his mother, Zinah Jennings, when they could not locate them. On Christmas Eve, Zinah Jennings was involved in a car accident. The responding officer noticed that Jennings was considered a missing person. Police say that when Jennings was questioned about her son, she gave "false and inconsistent information." Police also believe Jennings has ties to the Atlanta, Ga. and Charlotte, N.C. areas. There is a $10,000 reward for the safe return of Amir. Anyone with information is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Madeleine McCann

A combination of two pictures released by Madeleine McCann's spokesperson on May 1, 2009, shows Maddie McCann at the age of 3 (L), and an 'age progression' image of what she would look like at the age of 6. Madeleine McCann disappeared on May 3, 2007, just days before her fourth birthday, from the family's holiday apartment at the Portuguese resort of Praia da Luz. Her parents were dining with friends at a nearby restaurant when she went missing. The police force continues seraching the vanished little girl.

Joshua Davis

Joshua Davis, 2, was last seen at his New Braunfels, Texas, home on Feb. 4, 2011. He was watching the movie "Toy Story" with his mother when he left the room and vanished. The toddler's mother believes her son was abducted. Anyone with information on Joshua's whereabouts is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Sarah Kinslow

Sarah Elizabeth Kinslow, 14, was last seen by her parents on May 1, 2001, when her dad dropped her off at Greenville Middle School in her hometown of Greenville, Texas, at approximately 7:20 a.m. It was not until after the school day ended that the Kinslows were notified their daughter had not attended any of her classes. According to Louise Kinslow, her daughter had never run away in the past and was unprepared to be gone for an extended period of time when she went to school that day. Sarah Kinslow would be 25 years old today. At the time of her disappearance, she was 5-foot-4-inches tall, weighed 105 lbs., and had blonde hair and blue eyes. Her teeth were crooked and she had several ear piercings, a tattoo of the letter "I" on the inside of her ankle, a chicken pox scar on her left temple, and two chicken pox scars on her left cheek. Anyone with information is asked to call the National Center for Missing & Exploited Children at 1-800-843-5678 (1-800-THE-LOST) or the Greenville Police Department at 903-457-2900.

Khaniya Margarett Roberts

Khaniya Margarett Roberts, A.K.A. "Kiki," age 10, was last seen in Miami, Fla., on Dec. 3, 2011. She may be in the company of her mother. Anyone with information is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Brittanee Drexel

Brittanee Drexel, of Rochester, N.Y., was 17 years old in April 2009, when she went to Myrtle Beach, S.C., on spring break. The teen was last seen by friends on April 25 of that year, when she left the Bar Harbor Hotel in Myrtle Beach to meet friends at the nearby BlueWater Resort. Surveillance footage shows Drexel arriving at the resort, then leaving roughly 10 minutes later. What happened to her after that remains a mystery. Her cell phone gave off its last signal the day after she went missing. Investigators narrowed the phone location to an area near the South Santee River in Georgetown County. To date, no sign of Drexel has been found. At the time of her disappearance, Drexel was 5 feet tall and 103 pounds. She had blue eyes and blond highlights in her hair. Anyone with information in the case is asked to contact Myrtle Beach Police at 843-918-1382.

Trenton Duckett

In this photo released by the Florida Department of Law Enforcement is a portrait of Trenton Duckett, a 2-year-old boy who was reported missing on Aug. 27, 2006, from his home in Leesburg, Fla. The boy's mother Melinda Duckett, 21, was found dead from an apparent self-inflicted gunshot wound Friday, Sept. 8, 2006, at her grandparents' central Florida home, police said. Trenton's disappearance remains a mystery.

Sky Metalwala

An undated photo provided by the police in Bellvue, Wash. shows Sky Metalwala, 2, who has been missing since Sunday, Nov. 6. He disappeared after his mother says she left him alone in an unlocked car after it ran out of gas. She says she took her 4-year-old daughter with her and when she came back about an hour later, the boy was gone. (Bellevue Police / Seattle Times / AP)

Dwight Stallings

Dwight Stallings, 1, has been missing from Elk Grove, Calif., since April 2011. Authorities say the child has not been seen by family members and his mother, Tanisha Edwards, 35, has been unable or unwilling to reveal what happened to him. A $3,000 reward is being offered for information leading to the whereabouts of Dwight Stallings. Anyone with information is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Etan Patz

Etan Patz, 6, who went missing on May 25, 1979, near his home in New York's SoHo neighborhood, appears in this undated file photo. In June 2001, a New York State judge declared Etan legally dead, clearing the way for his parents, Stanley and Julie Patz, to file a wrongful death lawsuit against Jose Antonio Ramos, a Pennsylvania inmate whom the family believes sexually molested and then killed Etan. His parents were eventually awarded a "symbolic" sum of $2 million. Ramos is presently serving a 20-year sentence for child molestation and is scheduled to be released in November 7, 2012.

Malikah Beeks

Malikah Beeks, 17, of Cleveland Heights, Ohio, was last seen on April 11, 2012. Beeks is a possible runaway and may be with her 14-month-old son, Logan Beeks. Anyone with information on Beeks' whereabouts is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Ayla Reynolds

This undated photo obtained from a Facebook page shows missing toddler Ayla Reynolds. Police in Maine are appealing to the public for help in locating the 20-month-old girl who was last seen Friday night. Waterville Police Chief Joseph Massey held a news conference this afternoon to ask anyone with information about Ayla Reynolds to call police. Ayla's father called police yesterday morning to report that his daughter was not in her bed and couldn't be found. She was last seen sleeping at about 10 p.m. Friday by a family member.

Nadaysia McWhite

Nadaysia McWhite, 16, was last seen leaving her home in Queens Village, N.Y., on Feb. 19, 2012. McWhite never returned home and her whereabouts remain unknown. She was last seen wearing black pants, a black hooded coat and black boots. Anyone with information is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Kyron Horman

Kyron Horman was 7 years old when he disappeared on June 4, 2010. His stepmother, Terri Moulton Horman, told police she last saw the little boy walking to his classroom at Skyline Elementary School in Portland, Ore. The search for Kyron has become one of the most intense in recent Oregon history and has attracted national attention. His parents have held countless vigils, passed out thousands of fliers and issued numerous public pleas, all to no avail.

Reyna Guadarrama

Reyna Guadarrama, 9, was last seen in Grayslake, Ill., on Nov. 02, 2007. She may be in the company of her non-custodial mother and an adult male. They may travel to Mexico. Anyone with information is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Hailey Dunn

Hailey Dunn, a cheerleader, was last seen in Colorado City, Texas, just after Christmas Day in 2010. Dunn's mother, Billie Dunn, 34, reported her 13-year-old daughter missing on the morning of Dec. 28, 2010. The Colorado City Middle School student had been last seen the previous afternoon. Billie Dunn's then-boyfriend, Shawn Adkins, 25, told police that the teen was going to spend the night with a friend. That friend later told police that she had not made any plans for Hailey Dunn to spend the night and was unaware that the girl was coming over. Billie Dunn later told police she had fought with her daughter before she went missing. Colorado City Police, along with the Texas Rangers, the Mitchell County Sheriff's Office and other law enforcement departments in the region, conducted several searches for Dunn but found no sign of her.

Maayimuna Nyeeleni Njayi N'Diaye

Maayimuna Nyeeleni Njayi N'Diaye, 4, was last seen in Morehead, Ky., on Jan. 1, 2012. Maayimuna was allegedly abducted by her father, Ibrahim N'Diaye. A felony warrant was issued for him on Jan. 13, 2012. They are believed to be in Mali.

Haleigh Cummings

This photo released by the Putnam County Sheriff's Office shows Haleigh Cummings, 5, of Satsuma, Fla. Haleigh was last seen at home in the early-morning hours of Feb. 10, 2009. She was reported missing about 3:45 a.m. by Misty Croslin, the then-girlfriend of Haleigh's father, Ronald Cummings. Croslin told police she discovered Haleigh was missing when she woke up to use the bathroom. Law enforcement as well as private search-and-recovery groups have conducted multiple searches for Haleigh, but no sign of her has been found. Authorities have not named any suspects in the case; however, they say they have not ruled anyone out.

Kaylee Melara

Kaylee Melara, 17, was last seen in Braintree, Mass., on Jan. 14, 2011. Melara is biracial and has a tattoo on her upper right arm. Anyone with information is asked to contact the Black and Missing Foundation, at <a href="http://www.blackandmissinginc.com" target="_blank">blackandmissinginc.com</a>.

Source: http://www.huffingtonpost.com/2013/03/30/tobias-dustin-summers_n_2986450.html

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How To Do the Perfect Push-Up

Push-ups?we've all done ?em, but sometimes they just don't look so pretty. Fear not! We've got the guide to get it right. Push-ups are a total-body functional move that are great for increasing strength, much like bench-pressing, and have the added benefit of engaging the core and lower body (thanks, gravity!). The bodyweight exercise can be done just about anywhere?with a ton of variations to liven things up. So let's drop down and do the perfect push-up.

The Basics

1. Get into a plank position with hands planted directly under the shoulders (slightly wider than shoulder width apart). Ground the toes into the floor to stabilize the bottom half of the body. Engage the abs and back so the body is neutral. In other words, flat as a? plank (ah, now we get it!).

2. Begin to lower the body?back flat, eyes focused about three feet in front of you to keep a neutral neck?until the chest nearly touches the floor. (Note: Some experts say a push-up isn't a push-up unless the chest actually grazes the ground). Don't let the butt dip or stick out at any point during the move; the body should remain flat from head to toe all the way through the movement. Draw the shoulder blades back and down, while keeping the elbows tucked close to the body, so the upper arms form a 45-degree angle at the bottom of the push-up position.

3. Keeping the core engaged, exhale as you push back to the start position as explosively as possible without leaving the ground (pow!). That's one! Repeat for 10-20 reps or as many as can be performed with good form (no sagging those hips, ya heard?).

Variations

Changing the positions of both the elbows and hands will activate different muscles and amp up the intensity of the basic push-up. Ready? Here we go!

Bent Knee Push-Up: These push-ups are great for beginners to nail down form before graduating to other varieties. Come to all fours, hands directly under the shoulders. With the knees on the floor, lower to the ground the same way as a standard push-up, just with the knees helping to stabilize the body rather than the feet.

Alternating Med Ball Push-Up: This variety increases range of motion, and works core stability. Place one hand on top of the medicine ball, while the other stabilizes the body on the floor. Adjust the body into a plank (only this time, one arm is supported by the ball). Perform a standard push-up, then roll the ball to the other hand and repeat.

Single Leg Push-Up: This push-up is tricky, because the body is stabilized by only three points rather than four. Perform a standard push-up, but raise one leg up toward the ceiling, heel reaching toward the wall behind you. Alternate legs after each rep, or perform two sets (starting with one leg, then switching to the other for the next set).

Clap Push-Up: These push-ups are all about plyometrics, meaning the hands lift off the ground,, clap, then return to the floor. To break it down: Perform a standard push-up, but at the exhale, swiftly straighten the arms and forcefully push off the floor. Bring the hands together into a clap, then return to the start position. Note: This is not a beginner's exercise, and requires quite a bit of strength (and practice!) to perform correctly.

Handstand Push-Up: Handstands? Why not! These push-ups really amp up the demands. And we're not kidding, they take a lot of practice and coordination (and usually a wall, maybe even a spotter for your first go at it). Position the body against a wall and practice a static handstand before lowering into the push-up. Once you've mastered that, slowly lower the body down a few inches then press back up to a full handstand. Eventually, work toward lowering down completely to the floor before pushing back up. Carefully lower those legs and it's a wrap.

The Most Common Push-Up Mistakes (And How To Fix 'Em)

The Mistake: Focusing too much on the upper body.
The Fix: Sure, push-ups are known for strengthening the pecs, shoulders, and triceps, but they're a total-body move. Pay attention to the glutes and legs, and keep ?em tight! Tightening that tush can help keep the lower back from arching during the move. Instead of letting the bum flop down first (and compromising the lower back), hit the ground chest first, keeping the hips in the same plane as the shoulders. Imagine the belly button drawing in toward the spine to help keep the torso flat.

The Mistake: Flaring the arms.
The Fix: Letting those arms pop out to 90 degrees can be really tough on the shoulders. Instead of forming a "T" with the arms and body, keep the elbows tucked close to the body.

The Mistake: Forgetting to breathe.
The Fix: Faith Hill had it right: Just breathe. Concentrating on form and reps can make it easy to forget one of the most important parts of working out?breathing. Inhale on the way down, and exhale on the way back up.

The Mistake: Cheating Yourself.
The Fix: The key is quality over quantity. Make sure each push-up reaches a full range of motion by getting the chest as close to the floor as comfortable, then fully extending the elbows at the top. Having sloppy form will make for a less effective strengthening exercise that targets fewer muscles.

How To Do the Perfect Push-Up?Greatist

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Natalie McDermott tries her best to eat foods that make her feel good, but she has a lot of sweet teeth. She completed a 1-month ShakeWeight "challenge" ... well that was embarrassing... but she much prefers the gym with her coworkers or a hike in the woods. Nothing makes her happier than playing with puppies (and talking to them like they're human beings). She's a big fan of coloring, preferably with chalk or crayons.

Image remixed from BigStockPhoto and pixabay.

Want to see your work on Lifehacker? Email Tessa.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/6VGA62Qu3H4/how-to-do-the-perfect-push+up

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iPhone 5S announcement rumored for June 20th, launch in July

By Simon Evans MIAMI (Reuters) - World number one Serena Williams fought back from a set down to beat Maria Sharapova 4-6 6-3 6-0 and win the Sony Open for a record sixth time on Saturday as she continued her dominance over her closest rival. With the win, Williams, who struggled with her serve in the first two sets, becomes only the fourth woman in the Open era to win the same WTA tournament six times, joining Martina Navratilova, Chris Evert and Steffi Graf. "I finally have some record," Williams said. "Like it's really cool. I can't seem to catch up with Margaret Court or Steffi or ...

Source: http://news.yahoo.com/iphone-5s-announcement-rumored-june-20th-launch-july-145826634.html

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Demi Lovato back for "X Factor," 2 new judges yet to be announced

LOS ANGELES (Reuters) - Singer Demi Lovato will return as a judge on TV contest "The X Factor" for a second year, broadcaster Fox announced on Thursday, but there was no word on two more open positions on the celebrity panel.

The 20-year-old former Disney Channel star will be back in her seat when the show returns in the fall of 2013 along with creator Simon Cowell.

"I couldn't be happier that Demi wants to come back this year," Cowell said in a statement.

"She's a superstar in her own right and was a fantastic mentor last year. Even though she can be really, really annoying - I truly enjoyed working with her and so did the artists."

"X Factor" producers however have yet to announce replacements for departing judges Britney Spears and record producer Antonio "L.A." Reid, who quit at the end of the show's second season in December.

"There are going to be four judges," a source close to the show said on Thursday, but gave no details on who they might be or when the two new names would be announced.

Recent speculation on possible new judges for the U.S. version of the show have included singers Katy Perry, John Mayer, Pink and Ne-Yo.

Open auditions for singers hoping for a spot on the third season of "X Factor" are underway in cities across the United States. Auditions before the judges are expected to start in late May or early June.

Audiences for "X Factor" slumped in 2012, losing about three million viewers from its first season despite the hiring of Spears for a reported $15 million salary.

The show is just one of a plethora of singing and talent shows on U.S. television, including Fox television's long-running "American Idol," which has also seen a drop in viewers despite new judges Mariah Carey and Nicki Minaj, and NBC rivals "The Voice" and "America's Got Talent."

Fox is a unit of News Corp and NBC is a unit of Comcast Corp.

(Reporting By Jill Serjeant)

Source: http://news.yahoo.com/demi-lovato-back-x-factor-2-judges-yet-190044955--finance.html

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Facebook to hold Android event Thursday

NEW YORK (AP) ? Facebook has invited journalists to the unveiling of what it calls its "new home on Android."

Next Thursday's event will be held at the company's Menlo Park, Calif., headquarters. Facebook is not providing further details. There has been speculation that the company could launch a new phone, though that's unlikely.

Facebook is more likely to unveil a new Android app or some other integration into Android phones.

Citing unnamed sources, the tech blog TechCrunch says Facebook will launch a modified version of Android that embeds Facebook deeply into the operating system.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-03-29-Facebook-Android%20Event/id-6e18b56e3f194b73acd9b0da748906ca

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Points has an old putter and takes early lead

HUMBLE, Texas (AP) ? The march to the Masters for Rory McIlroy looks more like a crawl.

McIlroy only had four birdie putts on the front nine, none closer than 20 feet. He took two chips to reach the second green. He found the water on the third-easiest hole at Redstone Golf Club and made double bogey. What he salvaged Thursday in the Houston Open was a 73, along with some optimism.

"I think I'm still a little bit tentative on the golf course and not committing to my shots fully," McIlroy said. "But I think that just takes time and, hopefully, another three rounds this week and some good scores will give me confidence going into the Masters."

D.A. Points, using an old putter he once took from his mother, opened with five straight birdies on his way to an 8-under 64, giving him a one-shot lead over Cameron Tringale and John Rollins. Also coming to life was Angel Cabrera, the Argentine with two majors and a house at Redstone. He had a 66.

McIlroy, playing in the afternoon when the wind kicked up, was happy just to stay in range. Right when it looked as if the 23-year-old from Northern Ireland was headed for a big number, he rattled off three quick birdies and got it back to even par before he failed to convert a superb flop shot into par.

"I fought back well. I didn't get too down on myself," McIlroy said. "It would have been great to finish even par, but I made a couple of shots back, so that's not too bad."

Even so, the Houston Open is his final stop before the Masters, and it's not as if McIlroy has loads of rounds behind him. Thursday was only the ninth round he has completed in five tournaments this year. And he no longer has the No. 1 ranking, taken back by Tiger Woods last week at Bay Hill.

The first step is making the cut at Redstone on Friday, and seeing more good shots.

"My swing is not as free flowing because I'm working on a few things and getting into a couple of bad habits," McIlroy said. "But it's definitely feeling more natural than it has been the last few weeks."

Points first borrowed the Ping Anser from his mother during his junior years in Illinois, and like most golfers, he abandoned it once he stopped making putts. But he recently asked Ping to clean it up for him and add some weight. He also got a putting lesson ? no, not from Steve Stricker ? and he was on his way.

"Maybe I'm an idiot for not having used this putter the whole time," Points said. "It worked well today."

Points, whose only win came with actor Bill Murray at his side at the Pebble Beach National Pro-am, made all five of his opening birdies from inside 15 feet. He dropped only one shot along the way.

A mild wind gained strength in the afternoon, and Rollins still managed a 65.

"I knew the conditions were going to be tough out there, knew the greens were fast, so that makes it tough as well," Rollins said. "I just kept the ball in front of me and gave myself a lot of opportunities and got a solid round out of it."

Phil Mickelson was at 4 under and right in the mix until he hit his tee shot into the water on the sixth hole and made double bogey, nearly hooked a 3-wood into the hazard on the next hole and three-putted for bogey, and then made bogey on the par-3 ninth from a bunker to wind up at 72.

"It was a disappointing finish," Mickelson said. "I feel really good with the putter, and I believe that as the tournament goes on, I'll get better."

Mickelson played with defending champion Hunter Mahan, who didn't hit the ball his best and it finally caught up with him at the end for a 74. Also in the group was Geoff Ogilvy, who needs to finish in the top 50 in the world to get into the Masters. Ogilvy is currently at No. 50, though he will lose spots through the formula this week. He had three penalty shots in his round of 73.

Lee Westwood hit two shots in the water and still salvaged a bogey and was in the large group at 68 that included Riviera winner John Merrick and Jimmy Walker.

Charles Howell III had a 69 in his bid to get into his hometown major at Augusta National. Howell would need to finish at least in fourth place alone to have any chance of moving into the top 50.

Points was just trying to see some reasonable results, having made only two cuts all year. He did manage to join a group of stars in the Tavistock Cup earlier this week and, upon leaving home Tuesday, he grabbed a handful of putters. One of them once belonged to his mother.

Ping rep Matt Rollins had some weights added to the putter, and equally important was an impromptu lesson from Lamar golf coach Brian White.

"It's one of those things," Points said. "I holed some nice par putts yesterday in my pro-am. I didn't hit it great, but I made a few good putts and the ball was going in the hole with nice pace and rolling real tight. And I thought, 'All right, this might be the key that kind of gets me going.'"

That it did.

For McIlroy, it was another slow start. He has yet to break par in his five opening rounds this year ? that includes the Match Play Championship ? and found himself behind early. He was in a fairway bunker on the eighth hole, opened the face of 9-iron to advance the ball as far as he could, and caught the lip. With some 250 yards for his third shot, a 5-wood leaked into the water and he walked off with a double bogey.

But he never got down on himself.

"I think I learned from that over the last few weeks. I've got to keep my spirits up," McIlroy said. "I felt like I was doing that a bit too much at the Match Play and the Honda, and obviously we saw what happened there."

Frustrations boiled over at the Honda Classic halfway through the second round when McIlroy walked off the course. He vowed not to do that again.

Mickelson, meanwhile, was going along nicely despite some errant tee shots, such as his one on the 12th hole. He sliced the tee shot so far left that it bounced off the cart path, across the 13th tee box and down a slope toward the bushes. He was about pin-high, only 100 yards left of the green. He hit wedge into about 15 feet and turned to the gallery and said, "It's all about angles."

The angles caught up with him. Mickelson tee shot on the sixth never cleared the water, leading to his sloppy finish.

Source: http://news.yahoo.com/points-old-putter-takes-early-lead-195234612--spt.html

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Newtown Families in Bloomberg Anti-Gun Ads

Mayors Against Illegal Guns

The families of four victims from the December shooting at Sandy Hook Elementary appear in two new anti-gun TV ads out this morning, part of an effort to reinvigorate a lagging campaign for new gun controls.

"Don't let the memory of Newtown fade without doing something real," Terri Rousseau, the mother of slain teacher Lauren Rousseau, says in an emotionally charged appeal.

The ads also feature personal testimonials from Neil Heslin, father of 6-year-old Jesse Lewis; Chris and Lynn McDonnell, parents of 7-year-old Grace McDonnell; and Jillian Soto, sister of teacher Vicki Soto, 27. All talk about their loved ones and what it was like to learn the tragic news on Dec. 14, 2012.

You can see the spots HERE and HERE.

The ads, which will run only in Connecticut, come as that state's legislature considers state-level gun control measures. They were produced by NYC Mayor Michael Bloomberg's "Mayors Against Illegal Guns" and released in conjunction with a "National Day to Demand Action" taking place today across the country.

President Obama's outside advocacy group - Organizing for Action - is also part of the effort. More than 100 events are planned, organizers said.

At the White House later this morning, Obama will surround himself by victims of gun violence, their families and law enforcement officials to add his voice to the campaign. The Newtown families appearing in the ads are expected to attend.

The president and other advocates are still calling for legislation to impose comprehensive background checks; limits on high-capacity ammunition magazines; and an assault-weapons ban. But such measures face increasingly tough odds of passage in Congress.

Earlier this week, three Republican senators threatened to filibuster next month's expected Senate debate on a package of gun-control measures. That package does not include an assault-weapons ban, although Senate Democrats say it will get a vote as a separate amendment to the bill.

Also Read

Source: http://news.yahoo.com/newtown-families-bloomberg-anti-gun-ads-123407674--abc-news-politics.html

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Getting under the shell of the turtle genome

Thursday, March 28, 2013

The genome of the western painted turtle (Chrysemys picta bellii) one of the most widespread, abundant and well-studied turtles in the world, is published this week in Genome Biology. The data show that, like turtles themselves, the rate of genome evolution is extremely slow; turtle genomes evolve at a rate that is about a third that of the human genome and a fifth that of the python, the fastest lineage analyzed.

As a group, turtles are long-lived, can withstand low temperatures including freezing solid, can survive for long periods with no oxygen, and their sex is usually determined by the temperature at which their eggs develop rather than genetically. The painted turtle is most anoxia-tolerant vertebrate and can survive up to four months under water depending on the temperature. Turtles and tortoises are also the most endangered major vertebrate group on earth, with half of all species listed as endangered. This is the first turtle, and only the second non-avian reptile genome to be sequenced, and the analysis reveals some interesting insights about these bizarre features and adaptations, many of which are only known in turtles.

The western painted turtle is a freshwater species, and the most widespread turtle native to North America. Bradley Shaffer and colleagues place the western painted turtle genome into a comparative evolutionary context, showing that turtles are more closely related to birds and crocodilians than to any other vertebrates. They also find 19 genes in the brain and 23 in the heart whose expression is increased in low oxygen conditions ? including one whose expression changes nearly 130 fold. Further experiments on turtle hatchlings indicated that common microRNA was involved in freeze tolerance adaptation.

This work consistently indicates that common vertebrate regulatory networks, some of which have analogs in human diseases, are often involved in the western painted turtle achieving its extraordinary physiological capacities. The authors argue that the painted turtle may offer important insights into the management of a number of human health disorders, particularly those involved with anoxia and hypothermia.

###

BioMed Central: http://www.biomedcentral.com

Thanks to BioMed Central for this article.

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Source: http://www.labspaces.net/127506/Getting_under_the_shell_of_the_turtle_genome

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Good Friday Scoop

Good Friday Scoop

Jon Hamm Gets Penis Advice?[The Frisky] Barbara Walters Finally Retiring?[HollyWire] Justin Bieber Sets Record Straight on Battery Accusation?[Right Celebrity] Bacon Condoms Hitting Store Shelves??[The Celebrity Cafe] Anna Kendrick Trying Out a K-Pop Career?[The Blemish] Mariah Carey Wows with No Makeup?[The Huffington Post] Ashanti Denies Relationship with Nelly?[Girls Talkin Smack] Taylor Swift Guest Starring on “New ...

Good Friday Scoop Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2013/03/good-friday-scoop/

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2013 Wiley Prize to be awarded at Apr. 5 event

Public release date: 29-Mar-2013
[ | E-mail | Share ]

Contact: Peter Peretzman
sciencenewsroom@wiley.com
201-748-6098
Wiley

Winners to present important research on circadian rhythms

Hoboken, N.J. March 28, 2013 - Deborah E. Wiley, Chair of The Wiley Foundation, John Wiley & Sons, Inc. (NYSE: JWa & JWb) will present the 2013 Wiley Prize in Biomedical Sciences to Dr. Michael Young, Rockefeller University, Dr. Jeffrey Hall, Brandeis University (Emeritus), and Dr. Michael Rosbash, Brandeis University on Friday April 5.

The ceremony will take place at Caspary Auditorium, The Rockefeller University, 1230 York Avenue, New York, New York at 4:00 p.m. After receiving the award the three men will each present a brief lecture relating to their discovery of the molecular mechanisms governing circadian rhythms. The lecture will be streaming live here.

Studies of the molecular basis for circadian rhythmicity began more than thirty years ago in the lab of Dr. Young at Rockefeller University and Drs. Hall and Rosbash at Brandeis. Over the past three decades, the work of the three men focused on the fruitfly Drosophila melanogaster, with their research showing that the fly's circadian clocks are formed through the actions of a small group of genes.

These discoveries also apply to humans and other mammals, and could ultimately lead to the development of drugs to treat sleep disorders and jet lag, plus conditions associated with employees who work non-traditional shifts.

There is also evidence that the effectiveness of many drugs (including chemotherapeutics), our ability to fight infection, our ability to repair damaged tissues, and the incidence of certain forms of cancer depend on the proper working of circadian clocks. The Wiley Prize in Biomedical Sciences recognizes a specific contribution or series of contributions that demonstrate significant leadership in the development of research concepts or their clinical application. Particular emphasis is placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences.

The Wiley Foundation and the Wiley Prize in Biomedical Sciences were established in 2001.

###

About the Event:

The ceremony will take place at Caspary Auditorium, The Rockefeller University; 1230 York Avenue, New York, New York at 4:00 pm (EDT) The lecture will be streaming live at http://ds9.rockefeller.edu/wiley.

About Wiley

Wiley is a global provider of content-enabled solutions that improve outcomes in research, education, and professional practice. Our core businesses produce scientific, technical, medical, and scholarly journals, reference works, books, database services, and advertising; professional books, subscription products, certification and training services and online applications; and education content and services including integrated online teaching and learning resources for undergraduate and graduate students and lifelong learners.

Founded in 1807, John Wiley & Sons, Inc. (NYSE: JWa, JWb), has been a valued source of information and understanding for more than 200 years, helping people around the world meet their needs and fulfill their aspirations. Wiley and its acquired companies have published the works of more than 450 Nobel laureates in all categories: Literature, Economics, Physiology or Medicine, Physics, Chemistry, and Peace. Wiley's global headquarters are located in Hoboken, New Jersey, with operations in the U.S., Europe, Asia, Canada, and Australia. The Company's website can be accessed at http://www.wiley.com.

---

[ | E-mail | Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 29-Mar-2013
[ | E-mail | Share ]

Contact: Peter Peretzman
sciencenewsroom@wiley.com
201-748-6098
Wiley

Winners to present important research on circadian rhythms

Hoboken, N.J. March 28, 2013 - Deborah E. Wiley, Chair of The Wiley Foundation, John Wiley & Sons, Inc. (NYSE: JWa & JWb) will present the 2013 Wiley Prize in Biomedical Sciences to Dr. Michael Young, Rockefeller University, Dr. Jeffrey Hall, Brandeis University (Emeritus), and Dr. Michael Rosbash, Brandeis University on Friday April 5.

The ceremony will take place at Caspary Auditorium, The Rockefeller University, 1230 York Avenue, New York, New York at 4:00 p.m. After receiving the award the three men will each present a brief lecture relating to their discovery of the molecular mechanisms governing circadian rhythms. The lecture will be streaming live here.

Studies of the molecular basis for circadian rhythmicity began more than thirty years ago in the lab of Dr. Young at Rockefeller University and Drs. Hall and Rosbash at Brandeis. Over the past three decades, the work of the three men focused on the fruitfly Drosophila melanogaster, with their research showing that the fly's circadian clocks are formed through the actions of a small group of genes.

These discoveries also apply to humans and other mammals, and could ultimately lead to the development of drugs to treat sleep disorders and jet lag, plus conditions associated with employees who work non-traditional shifts.

There is also evidence that the effectiveness of many drugs (including chemotherapeutics), our ability to fight infection, our ability to repair damaged tissues, and the incidence of certain forms of cancer depend on the proper working of circadian clocks. The Wiley Prize in Biomedical Sciences recognizes a specific contribution or series of contributions that demonstrate significant leadership in the development of research concepts or their clinical application. Particular emphasis is placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences.

The Wiley Foundation and the Wiley Prize in Biomedical Sciences were established in 2001.

###

About the Event:

The ceremony will take place at Caspary Auditorium, The Rockefeller University; 1230 York Avenue, New York, New York at 4:00 pm (EDT) The lecture will be streaming live at http://ds9.rockefeller.edu/wiley.

About Wiley

Wiley is a global provider of content-enabled solutions that improve outcomes in research, education, and professional practice. Our core businesses produce scientific, technical, medical, and scholarly journals, reference works, books, database services, and advertising; professional books, subscription products, certification and training services and online applications; and education content and services including integrated online teaching and learning resources for undergraduate and graduate students and lifelong learners.

Founded in 1807, John Wiley & Sons, Inc. (NYSE: JWa, JWb), has been a valued source of information and understanding for more than 200 years, helping people around the world meet their needs and fulfill their aspirations. Wiley and its acquired companies have published the works of more than 450 Nobel laureates in all categories: Literature, Economics, Physiology or Medicine, Physics, Chemistry, and Peace. Wiley's global headquarters are located in Hoboken, New Jersey, with operations in the U.S., Europe, Asia, Canada, and Australia. The Company's website can be accessed at http://www.wiley.com.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-03/w-2wp032913.php

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Common gene variants explain 42% of antidepressant response

Mar. 28, 2013 ? Antidepressants are commonly prescribed for the treatment of depression, but many individuals do not experience symptom relief from treatment. The National Institute of Mental Health's STAR*D study, the largest and longest study ever conducted to evaluate depression treatment, found that only approximately one-third of patients responded within their initial medication trial and approximately one-third of patients did not have an adequate clinical response after being treated with several different medications. Thus, identifying predictors of antidepressant response could help to guide the treatment of this disorder.

A new study published in Biological Psychiatry now shares progress in identifying genomic predictors of antidepressant response.

Many previous studies have searched for genetic markers that may predict antidepressant response, but have done so despite not knowing the contribution of genetic factors. Dr. Katherine Tansey of Institute of Psychiatry at King's College London and colleagues resolved to answer that question.

"Our study quantified, for the first time, how much is response to antidepressant medication influenced by an individual's genetic make-up," said Tansey.

To perform this work, the researchers estimated the magnitude of the influence of common genetic variants on antidepressant response using a sample of 2,799 antidepressant-treated subjects with major depressive disorder and genome-wide genotyping data.

They found that genetic variants explain 42% of individual differences, and therefore, significantly influence antidepressant response.

"While we know that there are no genetic markers with strong effect, this means that there are many genetic markers involved. While each specific genetic marker may have a small effect, they may add up to make a meaningful prediction," Tansey added.

"We have a very long way to go to identify genetic markers that can usefully guide the treatment of depression. There are two critical challenges to this process," said Dr. John Krystal, Editor of Biological Psychiatry. "First, we need to have genomic markers that strongly predict response or non-response to available treatments. Second, markers for non-response to available treatments also need to predict response to an alternative treatment. Both of these conditions need to be present for markers of non-response to guide personalized treatments of depression."

"Although the Tansey et al. study represents progress, it is clear that we face enormous challenges with regards to both objectives," he added. "For example, it does not yet appear that having a less favorable genomic profile is a sufficiently strong negative predictor of response to justify withholding antidepressant treatment. Similarly, there is lack of clarity as to how to optimally treat patients who might have less favorable genomic profile.."

Additional research is certainly required, but scientists hope that one day, results such as these can lead to personalized treatment for depression.

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Story Source:

The above story is reprinted from materials provided by Elsevier, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Katherine E. Tansey, Michel Guipponi, Xiaolan Hu, Enrico Domenici, Glyn Lewis, Alain Malafosse, Jens R. Wendland, Cathryn M. Lewis, Peter McGuffin, Rudolf Uher. Contribution of Common Genetic Variants to Antidepressant Response. Biological Psychiatry, 2013; 73 (7): 679 DOI: 10.1016/j.biopsych.2012.10.030

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/z5l4WA6eDzU/130328091730.htm

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Record gene haul points to better cancer screening

By Ben Hirschler

LONDON (Reuters) - New research has nearly doubled the number of genetic variations implicated in breast, prostate and ovarian cancer, offering fresh avenues for screening at-risk patients and, potentially, developing better drugs.

The bumper haul of 74 gene changes that can increase risks for the three hormone-related cancers, announced by scientists on Wednesday, is the result of the largest ever study of its kind.

It follows an international project to analyze the DNA of more than 200,000 people - half of them with cancer and half from the general population - to find alterations that are more common in individuals with the disease.

Although each gene variation increases cancer risk by only a small amount, scientists calculate that the 1 percent of men carrying lots of the alterations could have a 50 percent increased risk of developing prostate cancer.

Women with multiple variants could see their risk of breast cancer increase by 30 percent.

Doug Easton of the University of Cambridge, one of the cancer researchers who led the work, said the batch of new genetic discoveries meant medical experts would be able to develop new cancer screening programs.

This will take time, since more research is needed to develop diagnostic tools.

"I would think that within five to 10 years this might be being used commonly, if not in a very widespread population base," said Paul Pharoah, also of the University of Cambridge.

Initially, the additional screening is likely to be targeted at patients with established cancer risk factors, such as carriers of BRCA gene faults. Women with BRCA faults are known to be at greater risk of developing breast and ovarian cancer.

NEW DRUGS

Ros Eeles of Britain's Institute of Cancer Research, an expert in prostate cancer, said the new findings were the biggest leap forward yet in understanding the genetic basis of the disease.

"They allow us, for the first time, to identify men who have a very high risk of developing prostate cancer during their lifetime through inheritance of multiple risk genetic variants," she said.

In the case of prostate cancer, scientists found 23 new genetic variations - known as single nucleotide polymorphisms, or SNPs - taking the total to 78. Significantly, 16 were linked with the more aggressive forms of the disease.

For breast cancer the researchers found 49 new SNPs, more than doubling the number previously identified, and in ovarian cancer the tally was 11.

A few of the variations were common to more than one cancer type, suggesting there may be common mechanisms of action that could be targeted by new drugs.

Developing medicines using the insight gained by the latest research will take many years, even assuming that drugmakers can produce compounds that work effectively. Encouragingly, though, companies such as Roche, the market leader in cancer, are getting better at making drugs that apply biochemical "brakes" to tumor cells.

The scientists stressed that genes, while important, were just one side of a complex mix of factors leading to cancer.

"Lifestyle and environmental risks act in concert with the genetics. It is not one or the other - it is always both together," Pharoah told reporters.

The new research was published in a series of papers in Nature Genetics, Nature Communications, PLOS Genetics, the American Journal of Human Genetics and Human Molecular Genetics.

(Editing by Anthony Barker)

Source: http://news.yahoo.com/record-gene-haul-points-better-cancer-screening-160348835--finance.html

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Fewer children mean longer life?

Mar. 27, 2013 ? New research into ageing processes, based on modern genetic techniques, confirms theoretical expectations about the correlation between reproduction and lifespan. Studies of birds reveal that those that have offspring later in life and have fewer broods live longer. And the decisive factor is telomeres, shows research from The University of Gothenburg, Sweden.

Telomeres are the protective caps at the end of chromosomes. The length of telomeres influences how long an individual lives. Telomeres start off at a certain length, become shorter each time a cell divides, decline as the years pass by until the telomeres can no longer protect the chromosomes, and the cell dies. But the length of telomeres varies significantly among individuals of the same age. This is partly due to the length of the telomeres that has been inherited from the parents, and partly due to the amount of stress an individual is exposed to.

?This is important, not least for our own species, as we are all having to deal with increased stress,? says Angela Pauliny, Researcher from the Department of Biological and Environmental Sciences at the University of Gothenburg.

Researchers have studied barnacle geese, which are long-lived birds, the oldest in the study being 22 years old. The results show that geese, compared to short-lived bird species, have a better ability to preserve the length of their telomeres. The explanation is probably that species with a longer lifespan invest more in maintaining bodily functions than, for example, reproduction.

?There is a clear correlation between reproduction and ageing in the animal world. Take elephants, which have a long lifespan but few offspring, while mice, for example, live for a short time but produce a lot of offspring each time they try,? says Angela Pauliny.

The geese studied by researchers varied in age, from very young birds to extremely old ones. Each bird was measured twice, two years apart. One striking result was that the change in telomere length varied according to gender.

?The study revealed that telomeres were best-preserved in males. Among barnacle geese, the telomeres thus shorten more quickly in females, which in birds is the sex with two different gender chromosomes. Interestingly, it is the exactl opposite in humans,? says Angela Pauliny.

The journal BMC Evolutionary Biology has classified the research article ?Telomere dynamics in a long-lived bird, the barnacle goose? as ?Highly Accessed?.

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Story Source:

The above story is reprinted from materials provided by University of Gothenburg, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Angela Pauliny, Kjell Larsson, Donald Blomqvist. Telomere dynamics in a long-lived bird, the barnacle goose. BMC Evolutionary Biology, 2012; 12 (1): 257 DOI: 10.1186/1471-2148-12-257

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/wo_0G9jQGjg/130327103045.htm

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Google picks 8,000 'Glass' winners

SAN FRANCISCO (AP) -- Google has picked out 8,000 people who will be given a chance to don a pair of Internet-connected glasses and make a fashion statement likely to be envied by gadget-loving geeks around the world.

The pool selected by Google won a contest conducted last month requiring U.S. residents to submit 50-word applications through Twitter or Google's Plus to explain how they would use a technology that is being hailed as the next breakthrough in mobile computing.

After sifting through a litany of ideas submitted with the hash tag "ifihadglass," Google Inc. began notifying the winners Tuesday.

Prevailing in this contest might not seem like much of a victory if you aren't a technology fan. The winners will have to pay $1,500 apiece if they want a test version of the product, which is called "Google Glass." They also will have to travel to New York, Los Angeles or the San Francisco Bay area to pick up the device, which isn't expected to be available on the mass market until late this year or early next year.

But getting a chance to be among the first to experience Google Glass is being treated like a hallowed privilege among the tech set. Some contestants even likened it to winning one of the five golden tickets that entitled children to a lifetime supply of candy and a visit at Willy Wonka's chocolate factory in the popular movie based on a book by Roald Dahl.

The excitement stems from the belief that Google Glass is at the forefront of a new wave of technology known as "wearable computing." Google, Apple Inc. and several other companies also are working on Internet-connected wristwatches, according to published reports that have cited anonymous people familiar with the projects.

Google Glass is supposed to perform many of the same tasks as smartphones, except the spectacles respond to voice commands instead of fingers touching a display screen. The glasses are equipped with a hidden camera and tiny display screen attached to a rim above the right eye.

The engineers who have been building Google Glass tout the technology as a way to keep people connected to their email, online social networks and other crucial information without having to frequently gaze down at the small screen on a smartphone. The hidden camera is designed to make it easy for people to take hands-free photos or video of whatever they are doing, whether it be bicycling, running, skiing, skydiving or just playing with friends and family.

Some of the winning entrants identified Tuesday by Google caught the company's attention by promising to put the camera to good use.

One contest winner promised to take Google Glass to Veteran Administration hospitals so soldiers who fought in World War II can see their memorials before they die. Another plans to wear Google Glass during a trip to Japan so she can take video and pictures that she can share with her grandmother, who now lives in the U.S. but would like to see her native country again. A zookeeper plans to use Google Glass to show what it's like to feed penguins, and another contest winner wants to use the technology to provide maps that will help firefighters in emergencies.

Privacy watchdogs, though, are already worried that Google Glass will make it even more difficult for people to know when they are on camera.

Google said the test, or "Explorer," version of Glass will help its engineers get a better understanding of how the technology might be used and make any necessary adjustments before the device hits the mass market.

The company, which is based in Mountain View, Calif., also sold an unspecified number of "Explorer" models to computer programmers last year. The finished product is expected to cost from $700 to $1,500.

Source: http://news.yahoo.com/google-picks-8-000-winners-220300460.html

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Nintendo video shows off Wii U speed improvement coming in April update

Nintendo's Wii U has faced complaints over slow loading and switching between menus since launch, but the company has promised a pair of updates will help the situation. Tonight it posted a video on YouTube (embedded after the break) that shows off the difference before and after the April update side by side. Showing off how quickly it can return to the home menu from a game of New Super Mario Bros. U, the updated console is ready to go in eight seconds, compared to the current software's 20-second delay. There's no mention of the other update to improve the speed of launching software, but hopefully that will be shown off soon as well. More than halving the main menu's load time is nothing to sneeze at, although it's still not exactly a snappy experience. We'll see if these tweaks -- once they arrive -- do anything to improve the console's position while it waits for the improved software lineup President Satoru Iwata is expecting.

Filed under: Gaming, HD, Nintendo

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Researchers discover the brain origins of variation in pathological anxiety

Tuesday, March 26, 2013

New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety. In a brain-imaging study to be published online today in the Proceedings of the National Academy of Sciences (PNAS), researchers from the University of Wisconsin School of Medicine and Public Health describe work that for the first time provides an understanding of the root causes of clinical variability in anxiety disorders.

Using a well-established nonhuman primate model of childhood anxiety, the scientists identified a core circuit that is chronically over-active in all anxious individuals, regardless of their particular pattern of symptoms. They also identified a set of more specialized circuits that are over- or under-active in individuals prone to particular symptoms, such as chronically high levels of the stress-hormone cortisol.

"These findings provide important new insights into altered brain functioning that explain why people with anxiety have such different symptoms and clinical presentations, and it also gives us new ideas, based on an understanding of altered brain function, for helping people with different types of anxiety,'' says Dr. Ned Kalin, senior author, chair of Psychiatry and director of the HealthEmotions Research Institute.

"There is a large need for new treatment strategies, because our current treatments don't work well for many anxious adults and children who come to us for help."

In the study, key anxiety-related symptoms were measured in 238 young rhesus monkeys using behavioral and hormonal measurement procedures similar to those routinely used to assess extreme shyness in children. Young monkeys are ideally suited for these studies because of their similarities in brain development and social behavior, Kalin noted. Variation in brain activity was quantified in the monkeys using positron emission tomography (PET) imaging, a method that is also used in humans.

Combining behavioral measures of shyness, physiological measures of the stress-hormone cortisol, and brain metabolic imaging, co-lead authors Dr. Alexander Shackman, Andrew Fox, and their collaborators showed that a core neural system marked by elevated activity in the central nucleus of the amygdala was a consistent brain signature shared by young monkeys with chronically high levels of anxiety. This was true despite striking differences across monkeys in the predominance of particular anxiety-related symptoms.

The Wisconsin researchers also showed that young monkeys with particular anxiety profiles, such as high levels of shyness, showed changes in symptom-specific brain circuits. Finally, Shackman, Fox, and colleagues uncovered evidence that the two kinds of brain circuits, one shared by all anxious individuals, the other specific to those with particular symptoms, work together to produce different presentations of pathological anxiety.

The new study builds upon earlier work by the Kalin laboratory demonstrating that activity in the amygdala is strongly shaped by early-life experiences, such as parenting and social interactions. They hypothesize that extreme anxiety stems from problems with the normal maturation of brain systems involved in emotional learning, which suggests that anxious children have difficulty learning to effectively regulate brain anxiety circuits. Taken together, this line of research sets the stage for improved strategies for preventing extreme childhood anxiety from blossoming into full-blown anxiety disorders.

"This means the amygdala is an extremely attractive target for new, broad-spectrum anxiety treatments,'' says Shackman. "The central nucleus of the amygdala is a uniquely malleable substrate for anxiety, one that can help to trigger a wide range of symptoms."

The work also suggests more specific brain targets for different symptom profiles. Such therapies could range from new, more selectively targeted medications to intensive therapies that seek to re-train the amygdala, ranging from conventional cognitive-behavioral therapies to training in mindfulness and other techniques, Shackman noted. To further understand the clinical significance of these observations, the laboratory is conducting a parallel study in young children suffering from anxiety disorders.

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University of Wisconsin-Madison: http://www.wisc.edu

Thanks to University of Wisconsin-Madison for this article.

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Source: http://www.labspaces.net/127463/Researchers_discover_the_brain_origins_of_variation_in_pathological_anxiety

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